|Salary:||£37,474 to £42,155|
|Placed On:||6th February 2023|
|Closes:||6th March 2023|
This post is full time (35 hours per week) and fixed term until 30April 2026
We are looking for a Research Associate to make a leading contribution to a project funded by the UKRI-Medical Research Council for 3 years, is to investigate the role of the orphan G protein-coupled receptor GPR35 in regulating lipid accumulation in liver and whether this may offer opportunities to target this receptor in diseases associated with fatty liver, including non-alcoholic steatohepatitis (NASH). As well as underpinning studies in cell models the work will assess this possibility both ex vivo and in vivo using novel, genetically engineered mouse lines. Parallel work employing both informatic analysis and direct studies on human tissue will be conducted with leading hepatologists at University of Edinburgh. The studies will build on our discovery that activation of GPR35 prevents, and indeed can reverse, lipid accumulation induced by various means in both hepatocyte-like cell lines and native hepatocytes isolated from wild type and transgenic mice (ACS Pharmacol. Trans. Sci. 4, 1835-1848).
Informal enquiries about the role are welcomed, and should be addressed to Professor Graeme Milligan (Graeme.Milligan@glasgow.ac.uk)
For more information on the University of Glasgow’s, School of Molecular Biosciences, please visit https://www.gla.ac.uk/schools/molecularbiosciences/
For more information and to apply online: https://my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.jobspec?p_id=108068
Closing date: 6 March 2023
It is the University of Glasgow’s mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.
We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equality.
The University of Glasgow, charity number SC004401.
Type / Role: