GMP Production Scientist - 2 posts

Nuffield Department of Surgical Sciences, Guy's Hospital, London

Contract type: Fixed-term for 24 months 

About the role

We are looking for two Production Scientists to work on the TWO Study, a Phase IIb trial of regulatory T cells in renal transplantation. This is a unique opportunity to become involved in an exciting research project using cell therapy in renal transplant recipients. 

You should note that, whilst the post is funded and employed by the University of Oxford, you will be required to work at the Guy’s and St Thomas’ NHS Foundation Trust and King’s College London GMP facility which is situated at Guy’s Hospital, London. 

Your role will be to prioritise and assist in the complete production process of manufacturing of clinical grade cellular therapy products for the TWO Study patients and to act as “champion” for the TWO Study in all aspects. In this key role, you will be responsible for all aspects of the process including, amongst other things, manufacturing of clinical grade cellular therapy products; labelling, documenting and storage of products according to product specification and quality standards; assisting in the appropriate qualification, process validation and regular re-validations required. You will also write SOPs relating to specific GMP facility and manufacturing operations and assist in the development and generation of product specific SOP’s and batch specific documentation. You will be expected to play a major role in generating data for reporting and analysis and for applications to the regulatory authorities.

About you

You will have a first degree in biomedical sciences and proven work experience in a laboratory/clean room setting, including techniques such as tissue culture, flow cytometry and cell manipulation/processing for clinical use. Experience in ‘Good Manufacturing Practice’ is essential for this role, as well as the ability to work both independently and collaboratively as part of a wider team. The ideal candidate will possess excellent IT skills, and will be able to confidently communicate their ideas in both verbal and written form.

These full-time posts are available immediately and are fixed-term for 24 months.

Application Process

If you would like to discuss this role please contact Fadi Issa: fadi.issa@nds.ox.ac.uk

Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA884 on all correspondence.

Only applications received before noon 1 March 2023 can be considered.

Interviews will be held 16 March 2023.

Committed to equality and valuing diversity.

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