Research Fellow in Molecular Biology and Imaging

Fixed Term Contract – 3 Years; Full Time - 35 Hours Per Week.

We are looking for an enthusiastic and motivated chromatin biologist to join Nick Gilbert’s research group (www.chromatinlab.org; @chromatinlab). Our group forms part of a vibrant research community within the MRC Human Genetics Unit where our specific focus is understanding how chromatin structure regulates gene expression and genome stability. Strong interest in chromatin biology and/or gene regulation is crucial whilst previous experience in molecular biology, genome-engineering, FISH, super-resolution microscopy and 3C/Hi-C techniques are desirable. 

The Opportunity:

This project aims to investigate how RNA-mediated large-scale chromatin structure affects transcription and will focus on a role for phase-separated protein/RNA structures. This is a unique opportunity for a PhD student or an experienced post-doctoral researcher to join a diverse team of chromatin biologists, physicists and bioinformaticians all investigating chromatin architecture and regulation.  

Your skills and attributes for success:

• PhD in a relevant subject.
• Strong interest in chromatin biology.
• Previous experience in FISH and/or super resolution microscopy.
• Molecular biology and tissue culture techniques including CRISPR, ChIP, RNAi, next generation sequencing.
• Ability to work independently and as a member of a collaborative team.

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