Back to search results

Post Doctoral Research Assistant

University of Dundee - Division of Cancer Research

Location: Dundee
Salary: £35,308 to £43,155
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 17th March 2023
Closes: 9th April 2023
Job Ref: 915

Full Time

Fixed-term until 30th September 2023

Grade 7 £35,308 - £43,155

We are recruiting for an exceptional individual to join us as a Postdoctoral Research Assistant within the Division of Cancer Research to study the role of RNA binding proteins in sarcoma cells. This position is fixed-term until 30th September 2023 but may be extended with onward funding being sought.

Post-doctoral researcher position available in the laboratory of Professor Kevin Hiom to study the role of RNA binding proteins in sarcoma cells. This exciting project builds on our recent findings that perturbations in mRNA processing with the generation of replication stress and impaired double strand break repair. We will use molecular and cellular biology as well as genetic and whole genome approaches to determine the key interactions of RNA splicing factors and mRNA processing proteins that might be targeted for the treatment of Ewing sarcoma patients. This is initially a one-year funded project with the potential for onward funding by Cancer Research UK/ SU2C. The position will also be supported by the appointment of a technician. The successful candidate can start as soon as possible.

The Hiom lab is in the state-of-the-art Jacqui Wood Cancer Centre at the University of Dundee, where there is a vibrant genome stability community. Dundee offers a great quality of life with good transport connections, coupled with a very reasonable cost of living.

Your priorities will include:

  • To carry out high quality lab-based research, working independently but contributing to the work and well- being of the group.
  • Work under the guidance of Professor Kevin Hiom but assume responsibility for leading and driving the project forward.
  • Undertake a variety of cell biology and molecular biology techniques, including preparation of genomic sequencing libraries.
  • Continually update knowledge by frequent reading of the literature to keep pace with technical developments and progress on the field.
  • Use initiative and creativity to problem solve difficulties, learn new techniques and identify new research areas.

Who we’re looking for:

  • Use molecular biology to examine the localization and interactions of DHX9 and BRCA1.
  • Use cellular and biochemical approaches including immunoprecipitation and high-resolution imaging to determine the role of RNA processing proteins in Ewing sarcoma.
  • Work with cell lines derived from sarcoma patients and develop reporter cell lines in tissue culture for analysis of protein-protein interactions.
  • Examine the efficacy of a potential DHX9 inhibitor

Appointment as a Postdoctoral Research Assistant on Grade 7 salary scale is dependent on candidate having a PhD, or may be considered on Training Grade 7 if you expect an award of a PhD.

The University of Dundee is a signatory of the Researcher Development Concordat and is committed to enhancing the research environment and culture. Engagement and support of activities which assist the researcher development agenda at the University is therefore essential.

Informal enquiries should be directed to Professor Kevin Hiom at k.hiom@dundee.ac.uk

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from University of Dundee

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge