Research Assistant

About us

The mission of the UCL GOS Institute of Child Health is to improve the health and well-being of children, and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-class education and training across a wide range of teaching and li! fe learni ng programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.

About the role

This is an excellent opportunity to work on a newly funded UKRI Medical Research Council (MRC) project. The successful applicant will be working as part of a newly set up group led by Dr Naresh Hanchate, who is a UCL Excellence Fellow and the holder of the MRC Neuroscience and Mental Health New Investigator Award. The aim of the Hanchate group is to investigate the impact of early life adversities on the brain circuitry, in particular, those that control physiological stress responses. The successful applicant will work together with the PI in helping the group setup murine studies, including the maintenance of transgenic lines, neurobehavioral and neurophysiological studies; and establishing state-of-the-art single nucleus transcriptomics, Connect-seq/n! uc-Connec t-seq, single-molecule FISH (RNA Fluorescent In situ Hybridization; RNAScope), in vitro cell culture, and eventually multimodal single-cell technologies (such as nucleus/ATAC seq), spatial transcriptomics and other techniques as they emerge. This post is available for 12 months (part-time) or 6 months (full-time) in the first instance and can be extended for an additional term of 12 months

About you

The successful candidate will have an honours degree in a biological Science, Experience in cellular and molecular biology techniques, experience in murine studies, including animal handling and maintenance of transgenic lines. Experience across different assay platforms, from cell-based to cell-free (e.g., ELISA), experience with mouse neurobehavioral and neuroendocrine analyses and current or previous holder of UK Home Office Personal License are desirable.

What we offer

Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out ! more. Our commitment to Equality, Diversity and Inclusion At GOS ICH we aim to always have a balanced interview panel that is representative of gender and ethnic diversity. We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level. UCL Taking Action for Equality If you have any queries regarding the application process, please contact Madhur Sharma on quoting job reference

Customer advert reference: B02-04878

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