Postdoctoral Research Fellow

Full time - 35 hours per week

Fixed term contract duration: 2 years, in first instance, with possibility of extension.

We are looking for a motivated postdoctoral researcher to conduct basic research into neuromodulatory (locus coeruleus) computation in mice, by utilizing a multimodal virtual reality system alongside in vivo electrophysiology, fibre photometry, and optogenetics.

The opportunity:

You will conduct research aimed at investigating prediction error responses and computation performed by the locus coeruleus in behaving mice. This will involve developing a novel multimodal virtual reality system for presenting and combining sensorimotor mismatch stimuli, and using fibre photometry and electrophysiology to record from the locus coeruleus. You will go on to use electrophysiology and/or widefield imaging, as well as optogenetics to interrogate the contribution of cortical activity to locus coeruleus computation.

Your skills and attributes for success:

• Appropriate degree with relevant post-graduate research experience. Usually a PhD (or PhD near completion) in Neuroscience/Physiology/Pharmacology or equivalent professional qualification and/or experience.
• Experience working with laboratory animals.
• Applicants must hold or be willing to obtain a Home Office Personal Licence (PIL) for working with mice.
• Good general knowledge of electrophysiological and optical techniques.
• Ability to communicate complex information clearly, orally, and in writing.

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