|£45,593 to £49,305 per annum
|6th November 2023
|3rd January 2024
Location: Hammersmith Campus
Contract: Fixed Term, Full time for 3 years with possibility for extension
Applications are invited for an exciting Postdoctoral Research Associate position in the laboratory of Professor Speck at Imperial College London (http://www.specklab.com/). This post aims to uncover fundamental and medically relevant mechanisms that guarantee efficient human DNA replication employing cutting-edge biochemical and structural approaches. The project’s primary objective is to discover 1.) how DNA replication origins are specified through epigenetic mechanisms and specific recruitment factors and 2.) how DNA replication is regulated to allow faithful DNA replication. The candidate will be able to take advantage of a recently established reconstituted system, which allows us to address these questions for the first time.
Who we look for:
We seek a creative researcher who enjoys tackling ambitious research questions. This project is ideal for a candidate who enjoys protein biochemistry, wants to learn cryo-EM/knows cryo-EM and wants to explore a new research area. Prior experience in the supervision of master students is an advantage. Professor Speck will mentor you in grant writing, networking and publishing.
Duties and responsibilities
You will express and purify proteins and use these in sophisticated biochemical assays. An interest in cryo-EM or existing expertise in structural biology would be beneficial. We are well equipped for biochemistry (multiple AKTAs) and electron microscopy (Talos 200kV FEG cryo-EM Falcon 3, Vitrobot IV, GPU- and data storage-cluster and direct access to a Titan Krios with K3 detector)
Essential and requirements
This is a Full Time and fixed-term role for 3 years initially based at the Hammersmith Campus.
Should you require further information please contact: Christian – email@example.com.
For technical issues when applying online please email firstname.lastname@example.org
The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/
The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.
Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.
Apply online via the above ‘Apply’ button.
Closing date: 03.01.2024
Type / Role: