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Research Assistant (80473)

Liverpool School of Tropical Medicine - Tropical Disease Biology

Location: Liverpool
Salary: £32,332 to £37,099 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 6th December 2023
Closes: 3rd January 2024
Job Ref: 80473

Full-time, fixed term appointment up to 18 months

Based in Liverpool

An exciting opportunity has arisen for a dedicated and enthusiastic Research Assistant to join the Team in the Tropical Disease Biology Department at LSTM.

Reporting to the Chair in Chair in Virology and Emerging Infectious Diseases, the successful candidate will support the studies of the comparative of wild type and attenuated pathogenesis of tick-borne encephalitis and louping ill viruses (TBEV/LIV). This part of the study will engineer by reverse genetics wild type and attenuated TBEV and LIV, and pathogenesis studies in mice, including determination of cytokine/chemokine markers during disease progression, are to be carried out. The ultimate aim is to obtain a comparative picture between the viruses, as well as how attenuation links to induction of immune responses compared to wild type, and what clues can be taken with regards to therapeutic interventions.

The successful post-holder will have experience with cell culture, molecular biology, virology (though microbiology and parasitology can be considered), and experience to support/work with murine infection models.

The project is part of a collaborative study with APHA and University of Nottingham on tick-borne flaviviruses.

Key deliverables will include (but not be limited to):

  • Develop and expand experiments for comparative analysis of TBEV and LIV pathogenesis: Support studies on reverse genetics production of wild type and attenuated TBEV and LIV; Support in vivo comparative infection studies in a mouse model; Support the analysis of host immune response induction across and between viruses.
  • Support reagent generation: Help maintain cell lines; mouse husbandry as appropriate; Virus design/reverse genetics and production of viruses.
  • Support the Research Group: Help in the provision of training in techniques in the lab; Assist in the support of student projects; Assist in training of staff in specific technologies or methods.
  • Project analysis and dissemination of research outputs: Contribute to research publication/scientific reports for donors; Contribute to the preparation and writing of scientific reports and peer-reviewed publications for the scientific community; Present results in group-internal meetings and to external collaborators.

The ideal candidate will have excellent interpersonal skills, with the ability and interest in working as an integral and cooperative member of a multi-disciplinary research team. Ideally you will be able to demonstrate:

  • Degree in Biology or related subject.
  • Experience in virology or microbiology or parasitology.
  • Experience in cell culture.
  • Experience in discussing/explaining research methods and technologies.
  • Excellent organisational skills.
  • Experience in animal work.

(Please refer to the full job description)

Informal enquiries can be made to: alain.kohl@lstmed.ac.uk

Additional benefits of joining LSTM:

  • 30 days annual leave, plus bank holidays, plus Christmas closure days
  • Generous occupational pension schemes
  • Government backed “cycle to work” scheme.
  • Affiliated, discounted staff membership to the University of Liverpool Sports Centre
  • Plus, a host of additional family friendly policies

Application Process: To apply for the position please click on the apply link and upload your CV and Covering Letter.

Due to the volume of applications, we receive, we may close our vacancies early, therefore please apply as early as possible.

Inclusion is central to our values at LSTM

LSTM actively promotes Equal Opportunities and Safeguarding Policies

Please note the Recruitment office will be closed from 20th December, and re-open on 2nd January 2024. 

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