Senior Research Scientist - Process Development
King's College London - Faculty of Life Sciences & Medicine - Gene Therapy and Regenerative Medicine
| Location: | London |
|---|---|
| Salary: | £51,974 to £53,350 per annum, including London Weighting Allowance. |
| Hours: | Full Time |
| Contract Type: | Fixed-Term/Contract |
| Placed On: | 2nd April 2024 |
|---|---|
| Closes: | 24th April 2024 |
| Job Ref: | 086987 |
Job Description
Role purpose
The KCL Centre for Gene Therapy & Regenrative Medicine (CGTRM) in collaboration with the KCL Gene Therapy Vector Facility (GTVF) develops and manufactures ATMPs for a wide variety of novel gene and cell therapies for the treatment of cancers to rare diseases. This is an opportunity to work within one of the largest academic GMP facilities in Europe focusing on the delivery of gene therapy products for early phase clinical trials.
In 2021 MRC/LifeArc/BBSRC announced the establishment of this Gene Therapy Innovation Hub. One of the main points of focus in the innovation component of the Hub will be the further development of new cell lines and vectors for the GMP compliant manufacture of viral vectors for the treatment of a host of acquired and inherited genetic disorders. The appointee will report to the Head of Process Development/ Senior Research Fellow.
Role profile
This role is for a qualified and experienced Research Scientist who has been working in an academic or commercial research laboratory/ company related to the development, manufacturing and purifiying viral vectors (lenti, retroviral) or other gene therapy products as IMPs.
The post holder will contribute to the plan to deliver technical innovation and lead specified work packages developing the experimental plan with the Head of Process Development and allocating resources to the tasks within the plan. To ensure successful development and translational of the work to GMP manufacture the candidate requires a strong background/ knowledge of viral vectors and purification methods and excellent interpersonal skills to work within and across diverse teams.
Additional experience in associated technologies, such as the use of bio-reactors, and concentration technologies for the production of viral vectors are essential.
This post will be offered on a fixed-term contract until 30th Sept 2026 in the first instance.
This is a full-time post - 100% full time equivalent.
Closing date: 24th April 2024
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