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PDRA in Innate Immunity

University of York - Biology

Location: Kingston upon Hull, York
Salary: £36,024 to £38,205 per annum. Grade 6
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 30th May 2024
Closes: 13th June 2024
Job Ref: 13374

Role

Applications are open for a postdoctoral research associate position (36 months) to perform lab-based research on inflammasomes function in human innate lymphoid cells in response to bacterial infections in Dr Dave Boucher research group (www.boucherlab.org). The project is based within the department of Biology and the York Biomedical Research Institute. The project is funded by a New Investigator Grant from the Medical Research Council.

Through the project, the PDRA will study the role of inflammatory caspases and the inflammasome pathway in controlling responses to infections in humans. The PDRA will build on strong preliminary data and use a combination of molecular techniques (e.g., western blot, cloning), cellular immunology (e.g., flow cytometry, Elisa), proteomics and high resolution microscopy. The candidate's professional development will be supported by strong mentoring and through access to various technical and professional training and conferences throughout the position. The candidate will evolve in a supportive, collaborative and multidisciplinary environment in immunology and haematology.

Skills, Experience & Qualification needed

We are looking for a candidate with skills in immunology and cellular biology.

  • A PhD in a relevant area (e.g., Immunology, Cellular Biology, or Biochemistry)
  • Experience with purification and handling of primary immune cells from human blood
  • Experience in handling and working with primary human innate lymphoid cells is desirable
  • Experience in cell culture and gene editing (desirable)
  • Experience performing and/or analysing proteomic experiments
  • Experience with fluorescence microscopy and flow cytometry is desirable.
  • Highly developed communication skills, attention to detail and commitment to high quality
  • Positive attitude to colleagues and students and a willingness to work proactively
  • Commitment to personal development and values of equality, diversity, and inclusion

The role is available on a fixed term basis for up to 36 months.

Interview date: To be confirmed

For informal enquiries: please contact Dr Dave Boucher, email dave.boucher@york.ac.uk.

The University strives to be diverse and inclusive – a place where we can ALL be ourselves.

We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.

We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork

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