Research Associate

About the role:

The Lloyd lab, funded by the Wellcome Trust, is conducting a multidisciplinary project to investigate neuro-immune-stromal interactions in response to environmental change, and how this drives allergic airway inflammation and remodelling.

We use patient samples and neonatal/adult allergic airway mouse models to determine immune-stromal interactions and assess their impact on disease progression, pathology, and lung function: www.lloydlab.co.uk.

This post will focus on immune cell phenotype and function and their interactions with the surrounding stromal environment, integrating data generated from a range of mouse models, live imaging of primary cells and matrisome analyses.

What you would be doing:

You will actively participate in the research programme of the Lloyd Group. You will conduct and plan your own scientific work, contributing independently to the group's research aims.

You will identify and develop techniques, software, and equipment for the collection and analysis of data. You will also assist in the supervision of students and research assistants, supporting their development and research activities.

You will be expected to publish in high-quality journals and to present data at national and international meetings.

What we are looking for:

The successful candidate will hold a PhD in a related discipline, demonstrate technical proficiency in a range of laboratory skills, and possess the ambition and drive to succeed.

This post will provide the opportunity to develop and drive a research project as well as writing up work for presentation and publication. Therefore, the ability to work independently and as part of a team, have excellent communication, organisational and problem-solving skills are essential.

• Extensive Flow Cytometry experience.
• Primary Cell Culture experience.
• Extensive Microscopy experience (Confocal, widefield, live cell imaging, intravital or IMC). Knowledge or experience of Second Harmonic Generation microscopy would be advantageous.
• Image Analysis and associated software including Image J, ICY, IMARIS, Huygens, Volocity, MCD, Cell Profiler, ilastik.
• Experience of single cell or bulk RNAseq, NGS, Spatial Transcriptomics or proteomics/mass spectrometry would be advantageous as would experience using R and/or python code for bioinformatics data analysis of multiplex datasets. Knowledge of MATLAB, Perl, CellPhoneDB, CellChat, NicheNet, Seurat.
• In vivo experience, preferably with a home office license - PIL A,B and C.

What we can offer you:

• The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
• Grow your career: gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression.
• Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).
• Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing.

Further Information

This is a full-time post (35 hours per week).

This role is for a fixed-term contract until June 2027.

If you require any further details about the role, please contact:

Laura Yates, Research Manager Lloyd Lab -  l.yates@imperial.ac.uk.

About Imperial

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