Research Assistant/Associate in Liver Fibrosis

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
We have an exciting opportunity to work on an MRC-funded project investigating the mechanistic role of PFKFB3 in Metabolic dysfunction associated steatohepatitis (MASH) and Liver cancer. The project is led by Professor Fiona Oakley in collaboration with Edinburgh University.

You will be embedded within the Newcastle Fibrosis Research Group in the Biosciences Institute at Newcastle University, and the project will involve tissue cultures of pre-clinical models and complex cell cultures (including ex vivo precision cut liver or tumour slice cultures), to explore the impact of cell-specific modulation of PFKFB3 to interrogate the disease biology to better understand the disease biology and identify new drug targets. The project will involve advanced histological, biochemical and molecular approaches.

You will be responsible for collection, processing, analysis, presentation (writing, graph production, image production and oral presentations at national/international conferences) and storage of experimental data in accurate, secure, detailed and up- to-date records of all work carried out to GLP standard.

You will use your knowledge and experience of liver fibrosis and liver cancer, in vivo models to deliver this challenging project.

This post is fixed-term until 15 June 2028.

For informal enquiries contact: Professor Fiona Oakley at fiona.oakley@newcastle.ac.uk.

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/.

Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

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