Postdoctoral Researcher in Chromosomal Instability
University of Oxford - Old Road Campus Research Building
| Location: | Oxford |
|---|---|
| Salary: | £39,424 to £47,779 Grade 7 |
| Hours: | Full Time |
| Contract Type: | Fixed-Term/Contract |
| Placed On: | 11th November 2025 |
|---|---|
| Closes: | 25th November 2025 |
| Job Ref: | 183260 |
About the role
The Lu lab is interested in the mechanism by which cancer karyotype mutates and becomes resistant to therapy, with the aim of finding new ways to treat cancer more effectively. We have recently highlighted the importance of the FAT1 gene during carcinogenesis (Lu et al, Nature Cell Biology 2025; Lu and Kanu, Nature Cell Biology 2025). We strive to understand the molecular mechanisms by which FAT protocadherins contribute to chromosomal instability and eventually shape cancer evolution.
We are seeking a highly motivated and ambitious Postdoctoral Researcher to join our team to functionally dissect how the mutations in FAT protocadherins contribute to chromosomal instability. You will be responsible for managing your own academic research and administrative activities. This involves small-scale project management and to co-ordinate multiple aspects of work to meet deadlines.
About you
You will hold a PhD/Dphil (or near to completion) in molecular biology or cancer biology with extensive knowledge and experience in DNA damage response field, cancer biology, or mechanobiology.
Possess technical expertise in advanced molecular biology techniques such as CRISPR, RNAi, DNA manipulation, microscopy, flow cytometry and quantitative real-time PCR.
You will have a strong track record of writing papers as evidenced by publications or submitted manuscripts in scientific journals, and have evidence of data presentation at scientific meetings
Application Process
The closing date for applications is noon on 25th November 2025
Interviews will take place on Friday 5th December 2025
What We Offer
As an employer, we genuinely care about our employees' wellbeing and this is reflected in the range of benefits that we offer including:
- An excellent contributory pension scheme
- 38 days annual leave
- A comprehensive range of childcare services
- Family leave schemes
- Cycle loan scheme
- Discounted bus travel and Season Ticket travel loans
- Membership to a variety of social and sports clubs
Committed to equality and valuing diversity
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