Postdoctoral Researcher in Chromosomal Instability

University of Oxford - Old Road Campus Research Building

Location:	Oxford
Salary:	£39,424 to £47,779 Grade 7
Hours:	Full Time
Contract Type:	Fixed-Term/Contract

Placed On:	11th November 2025
Closes:	25th November 2025
Job Ref:	183260

Location: Roosevelt Drive, Headington, Oxford, OX3 7DQ

About the role

We are seeking a highly motivated and ambitious Postdoctoral Researcher to join our team, with responsibility for dissecting the role of Fat protocadherins in cancer evolution.

The Lu lab is interested in the mechanism by which cancers' karyotypes mutate and evolve in the body and become resistant to therapy, with the aim of finding new ways to treat cancer more effectively. Using the data from the lung TRACERx consortium (Jamal-Hanjani et al NEJM 2017; Frankell et al Nature 2023) we have recently experimentally dissected how tumour evolution can be exacerbated by clonal driver alteration, through the combination of whole-genome doubling and chromosomal.

You will be responsible for managing your own academic research, and administrative activities, this involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines.

About you

You will hold a PhD/Dphil (or near to completion) in molecular biology or cancer biology with extensive knowledge and experience in DNA damage response field, cancer biology, or mechanobiology.

Possess technical expertise in advanced molecular biology techniques such as CRISPR, RNAi, DNA manipulation, microscopy, flow cytometry and quantitative real-time PCR.

You will have a strong track record of writing papers as evidenced by publications or submitted manuscripts in scientific journals, and have evidence of data presentation at scientific meetings

Application Process

Please apply via the ‘Apply’ button above.

The closing date for applications is noon on 25th November 2025

Interviews will take place on Friday 5th December 2025

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