Clinical Academic Fellow

Company description:

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Job description:

The Role

This role is focused on the deep phenotyping and multimodal data integration of a large cohort of mitochondrial disease patients with the aim of identifying key determinants of mitochondrial disease severity and progression.

The factors identified through this process will then be assessed for suitability as clinical biomarkers of disease progression for use in clinical trials or for clinical prognostication. It is also envisaged that these factors will influence clinical trial design and allow patient stratification in future trials of treatment. You will be supervised in this role by Dr Helen Devine and Prof Robert McFarland.

An integral element of this role is supporting patient recruitment and maintenance of the Mitochondrial Disease Patient Cohort (MitoCohort) database, one of the world's largest, most mature and comprehensive natural history studies on mitochondrial diseases. In addition, you will be expected to complement existing research activities within the Mitochondrial Research Group (MRG) and Newcastle University's Translational and Clinical Research Institute (NUTCRI) including the Mitochondrial and Neuromuscular theme and Rare disease NUCoRE.

The NHS Highly Specialised Service for Rare Mitochondrial Disorders is a nationally commissioned service covering diagnostic and clinical care for patients living with mitochondrial disease within the UK. It comprises three centres: Newcastle, London and Oxford. Prof McFarland, the chief investigator of MitoCohort is also the Director of the Highly Specialised Service for Rare Mitochondrial Disorders.

You will attend specialist clinics, multidisciplinary team (MDT) meetings and educational opportunities including acquiring new skill sets such as performance of conchotome muscle biopsies. You will also have the opportunity to liaise with other mitochondrial and neurology/medical specialists and external hospitals in providing advice for acute inpatient care as their experience grows. You will also actively contribute to clinical governance activities such as audits, quality improvement projects and mortality and morbidity meetings.

The candidate is expected to register for a PhD study.

This is a full time, fixed term position available for the duration of 3.5 years.

For all informal enquiries please contact: robert.taylor@newcastle.ac.uk

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