Laboratory Technical Specialist

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
Are you a laboratory technical specialist with a passion for stem cells and single cell genomics? Are you interested in joining a vibrant multi-disciplinary team working to understand in how mitochondrial DNA mutations affect people in different ways?

We are looking for a motivated technical specialist to join our dynamic research team, backed by significant funding from a recently awarded Wellcome Career Development Award. This is an exciting opportunity to collaborate with computational and wet-lab scientists at the forefront of pioneering research from the very start of a project. Our goal is to determine how the nuclear and mitochondrial genomes interact in mitochondrial DNA disease. You will harness the power of patient-derived stem cell models and large-scale single-cell genomics to address a fundamental question in the field of mitochondrial genomics - why do people who carry the same mitochondrial DNA mutation have such different disease outcomes?

In this role, you will be based at our Newcastle Upon Tyne campus, which has fantastic transport links and state of the art facilities. You will join the world-class, multidisciplinary Newcastle Mitochondrial Research Group, renowned for our extensive experience in characterising mitochondrial function in both health and disease. The group also includes a vibrant Young Scientists Group. Our researchers work in close collaboration with NHS clinical activities, bridging basic and translational science to advance the understanding of mitochondrial biology to develop new therapies for patients and families.

The position is full-time and available for a duration of 3.5 years in the first instance, starting in early 2026. We recognise and support diverse personal circumstances and are open to discuss flexible working arrangements.

To apply for the position, we’ll need your CV and a personal statement outlining how you are suitable for the role using evidence to highlight how you meet the essential criteria in the knowledge, skills and experience as listed in the job description (available on the university's website, accessed by the 'Apply' button).

Please focus your cover letter on the following key areas, outlining your ability and/or experience with:

• Culturing patient-derived cells, with an emphasis on iPSC experience.
• Preparing patient-derived samples for single cell genomics analysis.
• Providing general laboratory support.
• Collaborating regularly with team members to ensure high-quality research and the timely achievement of project goals.

For informal enquiries contact: Dr Sarah Pickett sarah.pickett@ncl.ac.uk.

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