Research Associate (Fixed Term)

We are seeking to recruit an experienced and well organised postdoctoral researcher to carry out research to understand transcriptional and functional changes as CTLs are activated by different stimuli. The research group is part of the Cambridge Institute for Medical Research on the Cambridge Biomedical Campus. The lab works on the molecular mechanisms that control killing by cytotoxic T lymphocytes, important cells of the immune system that kill virally infected and cancer cells. Our research combines cell biology and immunology, using genetic approaches including CRISPR and single cell RNA sequencing of primary lymphocytes, together with high-resolution imaging.

The holder of the post will be experienced in single cell RNA sequencing of primary lymphocytes and the impact of TCR signal strength on signalling pathways in naive and activated CTLs. Work will include handling primary cells, extracting RNA for experiments as well as coding required for analysis. The candidate must have published work in this area of biology and will need to write up work previously carried out in the laboratory.  Additionally, the candidate must be able to work with clinical colleagues in any collaborative projects.

The applicant must be a postgraduate in transcriptomic analysis and signal strength of CTLs, able to take part in clinical collaborations in this area. 

The Cambridge Institute for Medical Research (CIMR) is located on the Cambridge Biomedical Campus and it is a collaborative institute at the interface between fundamental research and the clinic, with a mission to determine the molecular mechanisms of disease in order to advance human health.

This post is available immediately and funding is available until February 2027 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.

We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

To apply online for this vacancy and to view further information about the role, please click the 'Apply' button above.

Closing date: 18th February 2026

Interview date: to be confirmed

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data) on our HR web pages.

Please quote reference SC48741 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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