Research Assistant

About us

The mission of the UCL GOS Institute of Child Health is to maximise and advocate for the holistic health of all children, young people and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. The 2024-29 GOS ICH strategy focuses on its five scientific programmes. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. The Institute offers world-class education and training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.

About the role

We are seeking a highly motivated Research Assistant to support a NIHR GOSH BRC-funded translational research project focused on developing advanced genome engineering strategies to investigate and correct disease-causing genetic variation in rare childhood neurological disorders. The role is primarily laboratory-based and embedded within a multidisciplinary team of scientists and clinicians working in a collaborative translational research environment. Hands-on experimental work using human induced pluripotent stem cells (hiPSCs), neuronal cultures, and brain organoid models. Genome engineering experiments and associated molecular analyses. Next-generation sequencing-based analysis to assess editing outcomes This role offers the opportunity to work on cutting-edge genome engineering research in human neuronal systems within a highly supportive academic and translational research environment. Please check Job Description/Person Spec for detailed information. This post is available for 12 months from 01/04/2026.

About you

You will have a Master’s degree in a relevant biological, biomedical, or life science discipline, with strong laboratory research experience. You will be confident working with aseptic mammalian cell culture techniques and core molecular biology methods. You will have substantial practical experience designing, executing, and evaluating gene editing experiments in mammalian cells, and contributing to the optimisation and implementation of gene editing workflows within a translational programme. Experience working with human induced pluripotent stem cells (hiPSCs), neuronal cultures, or 3D brain organoid models is desirable.

What we offer

Visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

Our commitment to Equality, Diversity and Inclusion

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/ If you have any queries regarding the application process, please contact Madhur Sharma on ich.hr@ucl.ac.uk.

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