Postdoctoral Research Associate in Ubiquitin E2 Mechanisms

Location: Department of Biochemistry, South Parks Road, Oxford OX1 3QU

About the role

The post holder will be a member of a dynamic and growing research group under the supervision of Associate Professor Paul Elliott in the Department of Biochemistry, University of Oxford. The postholder will be responsible for managing an independent project investigating the mechanisms of cell death, specifically the activity and regulation of several ubiquitin ligases, using a combination of protein biochemistry, biochemical, biophysical and structural biology assays. The post holder is expected to provide guidance and support within the research group to fellow postdocs, DPhil students and undergraduate project students, maintaining a strong collegiate environment.

This full-time fixed-term post is funded by the Cancer Research UK for up to 12 months in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You will hold or be near completion of a PhD/DPhil and have a strong background in protein expression and purification techniques, with a good understanding of the ubiquitin system. You should have experience using in vitro ubiquitination assays and have a strong background in structural biology: X-ray, NMR or cryoEM. You will have proven experience of developing small-molecule screening assays and a background in biophysical techniques for measuring protein-protein and/or protein-ligand interactions. Excellent written and oral communication skills, with the ability to work with colleagues and students is essential.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including: 

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Application Process

Applications for this vacancy are to be made online via the 'Apply' button above and Vacancy ID 186164. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Click here for information and advice on writing an effective Supporting Statement.  As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the How to apply section of the job description. Any further enquires may be directed to recruitment@bioch.ox.ac.uk.  

The closing date for applications is 12.00 noon on Monday 18^th May 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter. 

Committed to equality and valuing diversity

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