Postdoctoral Research Associate in ubiquitin signalling

Location: Department of Biochemistry, South Parks Road, Oxford OX1 3QU

About the role

The post holder will be a member of a dynamic and growing research group under the supervision of Associate Professor Paul Elliott in the Department of Biochemistry, University of Oxford. The postholder will be responsible for managing an independent project investigating the mechanisms of FAT10ylation, a poorly understood form of post-translational modification. The post holder is expected to provide guidance and support within the research group to fellow postdocs, DPhil students and undergraduate project students, maintaining a strong collegiate environment.

This full-time fixed-term post is funded by the Cancer Research UK for up to 12 months in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

About you

You will hold a PhD/DPhil and have a strong background in protein expression and purification techniques, together with a thorough understanding of the ubiquitin system and practical experience performing in vitro ubiquitination assays. You will demonstrate expertise in at least one structural biology approach, including X-ray, NMR, or cryoEM, alongside proven experience of mammalian cell culture techniques. You will possess excellent written and verbal communication skills, with the ability to publish high-quality research in peer-reviewed journals and maintain accurate and detailed records. You will be a collaborative researcher with excellent interpersonal skills, able to work with colleagues and students. Experience using CRISPR/Cas9 systems to translate structural findings into mammalian cell-based assays, a strong background in E3 ubiquitin ligases, and the use of biophysical techniques to investigate protein-protein interactions and complex stoichiometry would be advantageous.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family-friendly and financial benefits including:

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

Application Process

Applications for this vacancy are to be made online via www.recruit.ox.ac.uk and Vacancy ID 187637. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. Click here for information and advice on writing an effective Supporting Statement. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please refer to the How to apply section of the job description, click the 'Apply' button above. Any further enquires may be directed to recruitment@bioch.ox.ac.uk.  

The closing date for applications is 12.00 noon on Monday 3^rd August 2026. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held as soon as possible thereafter.

Committed to equality and valuing diversity

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