Postdoctoral Research Scientist in dopamine neuron physiology in Parkinson’s

About us:

At the Department of Physiology, Anatomy & Genetics (DPAG), we undertake world-leading discovery science, investigating physiological processes at the molecular, cellular, tissue and systems levels. Our research bridges fundamental science and translational medicine, connecting the physical and life sciences. We are committed to innovative research, excellence in teaching, and fostering an inclusive and supportive working environment.

Overview of the role:

We are seeking a Postdoctoral Research Scientist to join Professor Stephanie Cragg’s research group on a Parkinson’s UK-funded project investigating receptor neuromodulation of dopamine neuron physiology. The successful candidate will study how non-canonical glycine receptors influence midbrain dopamine neuron function and dopamine transmission in health and animal models of Parkinson’s disease. This full-time post is available from 1 November 2026 to 31 October 2029.

Key responsibilities:

• Work with the grant holders to deliver high-quality research using real-time electrophysiological and imaging techniques to record dopamine neurons and dopamine release in ex vivo brain slices.
• Apply complementary methods including stereotaxic intracranial vector delivery, pharmacological manipulations, systemic dosing, immunohistochemistry, microscopy, and molecular analyses of animal and human brain tissue.
• Help manage and genotype transgenic animal colonies and Parkinson’s disease models.
• Contribute to the training and supervision of other group members.

Selection criteria:

• Hold, or be close to completing, a PhD/DPhil in a relevant area of neurobiology or neuroscience.
• Expertise in electrophysiological recording techniques in animal model brain slices.
• Experience investigating central nervous system circuits and conducting stereotaxic surgeries.
• A strong publication record demonstrating originality, creativity and productivity in neuroscience research.
• Commitment to open science practices.

What we offer:

• Excellent contributory pension scheme
• 38 days annual leave
• Childcare support and family leave schemes
• Cycle and electric car loan schemes
• Employee Assistance Programme
• Social and sports club membership opportunities
• Discounted travel schemes

How to apply:

Submit a CV, supporting statement addressing the selection criteria, and details of two referees. Applications close at 12 noon on 21 September 2026. Interviews are expected during the week commencing 5 October 2026. DPAG particularly welcomes applications from women and Black and minority ethnic candidates and is committed to equality, inclusion and sustainability.

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