Senior Laboratory Research Scientist - Flow Cytometry

Location: The Francis Crick Institute, London

Short summary

We are seeking an experienced Flow Cytometry Specialist to join our team and help deliver an outstanding service to researchers across the Crick. 

You will provide expert advice on experimental design, multicolour and spectral flow cytometry, cell sorting and data analysis, while operating and maintaining a wide range of advanced instrumentation. A key part of the role will also be hands-on troubleshooting – from optimising the latest technologies to maintaining complex legacy instruments that require creative technical problem-solving.

Key Responsibilities 

These include but are not limited to:

• Providing expert scientific and technical advice to researchers using flow cytometry.
• Supporting experimental design, multicolour and spectral panel design, assay optimisation and troubleshooting.
• Operating, maintaining and troubleshooting high-speed cell sorters and multi-laser analysers.
• Supporting the introduction, validation and optimisation of new technologies and workflows.
• Analysing and interpreting flow cytometry data using specialist software and computational tools.
• Training and mentoring researchers and junior team members in flow cytometry best practice.
• Supporting laboratory operations, documentation, equipment management and continuous improvement across the facility.

About you

You will have:  

• A PhD with at significant practical experience in flow cytometry, or a BSc (Hons) with substantial relevant experience gained within a core facility, research or company setting.
• Extensive hands-on experience operating high-speed cell sorters and multi-laser analysers.
• Experience supporting flow cytometry experimental design, multicolour panel design and troubleshooting.
• Experience with spectral flow cytometry.
• Strong technical ability and enthusiasm for maintaining and troubleshooting complex flow cytometry instrumentation.
• Proficiency with flow cytometry acquisition and analysis software such as FACSDiva and FlowJo.
• Experience developing SOPs and risk assessments and training or mentoring researchers.
• Excellent communication, organisational and collaborative working skills.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it to the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

To apply for this role, please click on the 'Apply' button above.

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