Location: | London |
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Salary: | £43,093 to £50,834 per annum |
Hours: | Full Time, Part Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 22nd March 2024 |
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Closes: | 30th April 2024 |
Job Ref: | MED04368 |
Location: White City Campus
Job Summary
The Ye lab invites applications from talented, highly motivated, and ambitious postdoctoral scientists for a Research Associate position leading one or more projects exploring the role of proteasomes in the clearance of toxic aggregates derived from pathological samples. The project will unveil factors that assist proteasomes in removing amyloidogenic proteins in healthy cells and the malfunction of proteasomes in pathological cells. You will use a multidisciplinary approach (maintenance and manipulation of IPSC-neurons and established cell lines, fluorescence imaging and various biochemical techniques) to identify the types of modifications and potential factors that are associated with proteasomes during cell stress induced by pathological protein aggregates.
Please contact Dr Yu Ye – yu.ye1@imperial.ac.uk for a discussion about the project and role.
This role is part of the Department of Brain Sciences at Imperial College London, located in. Postdocs in the Ye lab at Imperial enjoy excellent career development opportunities with:
Duties and responsibilities
As a Research Associate in the Ye lab, you will:
Essential requirements
You are a motivated and organised researcher, excited by the science we do.
With (or near completion of) a PhD in Cellular Neuroscience and/or IPSC cultures (or related discipline), you will be strongly objective-driven, able to lead the project independently and put new knowledge into practice effectively.
Experimental expertise working with IPSC-differentiated neuronal culture, basic biochemistry and molecular biology is essential. Experience with advanced microscopy is a bonus.
Practical experience of quantitative image analysis, mass spectrometry or coding research projects is highly desirable in the lab.
Further Information
This position is offered full or part time, up to three-years and is based at the White City.
Applicants who have not yet had their PhD degree awarded will be appointed to the Research Assistant scale.
For issues related to the online application, please contact s.jobs@imperial.ac.uk
Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.
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