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Research Fellow

University College London - Research Department of Genetics, Evolution and Environment, Institute of Healthy Ageing London

Location: London
Salary: £35,328 to £37,281 Per annum, inclusive of London Allowance
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 19th June 2019
Closes: 19th July 2019
Job Ref: 1811362

UCL Division of Biosciences

The appointment will be on UCL Grade 7.

The research in the Alic laboratory aims to understand how transcription underpins the plasticity of adult physiology and lifespan in the fruit fly. We are interested in a range of components of the eukaryotic transcriptional apparatus, from basal transcriptional machinery (see Filer et al. 2017 Nature 552:263–267) to specific transcription factors (see Dobson et al. 2017 Cell Reports 18:299-306) and their role in adult physiology, health and lifespan. The laboratory is part of the Institute of Healthy Ageing, an interdisciplinary centre of excellence for research on the biology of ageing and ageing-related diseases.

The main objective of this BBSRC-funded project is to elucidate the molecular mechanisms whereby partial inhibition of RNA polymerase III can extend lifespan in the fruit fly. The long-term aim of this work is to ensure human health and wellbeing throughout the life course. The project will be conducted in collaboration with the laboratory of Dr Jennifer Tullet at the University of Kent and Prof. Colin Selman at the University of Glasgow.

The post holder will be an active member of a research team assisting in the development, planning and delivery of the research activity within a specified area so that the overall research objectives of the project are met. The post holder will be expected to produce independent, original contributions to the subject area.

This post is available to start immediately and is funded until 31st August 2021 in the first instance with a possibility to extend for up to 1 year.

The successful candidate will have a PhD (or be close to obtaining) in a relevant subject area e.g. Biochemistry, Molecular Biology or Genetics and have extensive experience of working in a research environment.

The researcher joining the laboratory will also have a proven knowledge of research techniques and methodologies in either transcription, or Drosophila physiology and/or genetics, ageing, or genomics techniques and/or analysis.

The post holder must have laboratory research skills in some relevant areas such as nucleic acid and protein purification, detection, manipulation, Drosophila handing, genetics, Drosophila dissections, transcriptomic or transcriptional analysis.

Furthermore, the successful candidate will have a strong publication (submitted or accepted) and academic record and the ability to present complex information effectively to a range of audiences.

Please note: Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £30,922 - £32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis (including corrections) 

UCL vacancy reference: 1811362

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

For informal queries regarding the vacancy, please contact Dr Nazif Alic, If you have any queries regarding the application process, please email quoting the advert reference number 1811362 in the subject line.

Latest time for the submission of applications: 23:59.

Interview Date: TBC

UCL Taking Action for Equality

We will consider applications to work on a part-time, flexible and job share basis wherever possible.

Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.

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