Back to search results

Postdoctoral Scientist in Leukaemia Biology

University of Oxford - Radcliffe Department of Medicine

Location: Headington, Oxford
Salary: £33,309 to £40,927 per annum Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 24th November 2021
Closes: 6th December 2021

An exciting opportunity has arisen for a highly motivated and ambitious Postdoctoral Scientist to join Professor Paresh Vyas and Professor Irene Roberts at the MRC Weatherall Institute of Molecular Medicine (WIMM). You will be based in the Vyas laboratory and will work with both Professors Vyas and Roberts, as well as other research groups based at the WIMM.

The Vyas and Roberts laboratories are world-leading in the study of the biology of acute myeloid leukaemia using paediatric leukaemia as a model. We have focussed on the myeloid leukaemia in children with Downs syndrome who have a 150-fold increased incidence of leukaemia. Through a comprehensive study of the genetics, functional studies including CRISPR-based screens and targeted loss of function studies combined with single cell biology, in primary patient samples and in vivo models, the successful applicant will now dissect how multiple leukaemic mutations cooperate to perturb blood stem and progenitor cell differentiation, with the aim of understanding fundamental principles of how genetic and epigenetic change causes arises leukaemia and that will provide a platform for rational therapy.

You will hold a PhD (or near to completion: thesis submitted at time of application) in leukaemia biology, the study of haematopoiesis or transcription factor function. You will have laboratory experience in FACS analysis and sorting, CRISPR, cell culture, single cell biology, working with in vivo models and computational experience in analysis of transcriptomic and epigenetic datasets. A strong publication record in high-impact peer-reviewed journals is a prerequisite, as well as the ability to work independently and as part of a team. You will have excellent communication and organisational skills, with the ability to manage and independently drive, innovate and complete your own research and associated activities.

This post is fixed term until 10/01/2024, funded by Blood Cancer UK.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is 12 noon on Monday 06 December 2021.

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from University of Oxford

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge