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Research Assistant in Induced Pluripotent Stem Cell (iPSC) Models to Support Parkinsons Drug Discovery, Oxford-GSK Institute of Molecular and Computational Medicine

University of Oxford - Wellcome Centre for Human Genetics

Location: Oxford
Salary: £30,502 to £36,386 p.a. Grade 6
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 5th December 2022
Closes: 13th January 2023
Job Ref: 162149

Location: Wellcome Centre for Human Genetics, Roosevelt Drive, Old Road Campus, Headington, Oxford, OX3 7BN

Salary: Grade 6: £30,502 - £36,386 with a discretionary range to £39,745 p.a.

We are seeking to appoint a high motivated Research Assistant to join the newly established multidisciplinary Oxford-GSK Institute for Molecular & Computational Medicine (IMCM) operating within the Nuffield Department of Medicine (NDM) in collaboration with Nuffield Department of Clinical Neuroscience (NDCN), Nuffield Department of Population Health (NDPH) and Department of Physiology, Anatomy and Genetics (DPAG). 

The Institute will bring together the very best scientific, clinical, technological and computational expertise from Oxford University and GSK to form unique industry/academic partnership. The aim of the institute is to improve tools in, and knowledge from, genetics, genomics, molecular and single cell biology, spatial imaging, machine learning and novel methods of data handling to study the pattern of diseases in new ways. Researchers working under IMCM will be allocated to specific projects in the first instance, however, maybe reallocated to other IMCM projects in the future appropriate to the researcher’s experience and skill set. You will be employed by the University of Oxford, and must be willing to work on a cross-cutting departmental basis (currently DPAG, NDPH, NDM and NDCN) depending on scientific phasing of the IMCM projects. 

Reporting to Professor Richard Wade-Martins, you will be required to support the generation and characterision of induced pluripotent stem cell (iPSC) lines within the DPAG team in the first instance. This job involves performing iPSC generation by iPSC reprogramming; picking and expanding iPSC clonal lines; use of liquid handling automation; iPSC line expansion, maintenance, quality control, freezing and thawing. You will be responsible for maintaining excellent record and database management to track the iPSC reprogramming process from fibroblast through to multiple frozen clonal iPSC lines. 

It is essential that you hold BSc degree in neuroscience or cell/molecular biology, and have experience in cell culture, preferably with human stem cells. Knowledge of neurodegenerative diseases, such as Parkinson’s or Alzheimer’s is essential and you will be able to conduct high quality research, manage time and work to strict deadlines. It is essential that you have excellent record keeping and database management, and excellent communication skills, both verbal and written.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract for 5 years and is funded by GSK. 

Only applications received before 12 midday on 13 January 2023 will be considered. Please quote 162149 on all correspondence.

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