Research Assistant Positions

Harwell Campus, Oxfordshire

Full Time (36 hours per week)

About us

The Mary Lyon Centre at MRC Harwell (MLC) https://www.har.mrc.ac.uk/ is located in an expanding science and innovation park in Oxfordshire and is an internationally renowned centre at the forefront of genetics research.  As the hub of the new National Mouse Genetics Network, the specialist facilities and capabilities of the MLC support a number of distinct research clusters spread across the UK to accelerate our understanding of human disease.

About the Role

The available posts are based within established laboratories involved in the generation and quality control of mouse targeted alleles and genotyping at the MLC. The laboratories use a range of molecular biology techniques including generation of CRISPR reagents, PCR, Sanger sequencing analysis, droplet digital PCR, non-radioactive Southern blotting, qPCR-based genotyping and embryonic stem (ES) cell culture.

We have two exciting positions for Research Assistants to join our Molecular and Cellular Biology (MCB) team. Among this range of techniques, the post-holders will focus in particular on employing ddPCR for genomic or functional validation of new alleles generated by the service.

You may also be required to apply other molecular techniques in support of the genome engineering activity.

Previous experience of ddPCR will be an advantage, but not essential as training can be provided.

Key Responsibilities

• Characterisation and quality control of genetically modified materials,6 employing PCR-based techniques. Genotyping. Sample management and communication of results.
• Other general duties required are to ensure the smooth running of a molecular biology laboratory; e.g., ordering reagents – tasks shared with the rest of the team.
• Process samples/tasks and work with the other MCB team members.

About You:

You will have:

• A BSc in Biological Sciences or related subject and an understanding of basic techniques; e.g., qPCR and ddPCR.
• Experience of working in a laboratory.
• Experience in basic techniques of molecular biology; e.g., PCR, cloning, DNA sequence analysis, ddPCR.
• An understanding of genetic modification in laboratory animals.
• You will be organised and hard-working, with precision and a strong eye for detail, and will be able to work well as part of a team.

For the full job description, please visit our site at the link below.

Benefits:

Choosing to come to work at the MRC (part of UK Research and Innovation (UKRI)) means that you will have access to a whole host of benefits, from a defined-benefit pension scheme and excellent holiday entitlement, to access to employee shopping/travel discounts and a salary sacrifice cycle-to-work scheme. In addition, you will have the opportunity to contribute to the work of a world-class medical research organisation and to acquire professional registration.

How to Apply:

For full details and to apply please click the 'Apply' button above. Please quote reference MLC 2122

The closing date for applications is 12-Apr-2023

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