Post-doctoral Scientist in Cancer Immunology

Group: Liver Regeneration & Tissue Engineering, & Liver Immunology

Reporting to: Dr Luca Urbani (PI) and Prof Shilpa Chokshi (PI and Acting Director)

Duration: 2 years initially, possibility of extension

Annual leave: 27 days per annum

Starting date: June 2024

We are seeking an ambitious and motivated post-doctoral scientist to become an integral part of the Liver Regeneration and Tissue Engineering group and Liver Immunology group at the Roger Williams Institute of Hepatology (RW-IoH). Do you have the passion to explore the frontiers of knowledge in cancer immunology and extracellular matrix (ECM) research?

As a key team member you will spearhead a groundbreaking project exploring immunomodulatory properties of the extracellular matrix in hepatocellular carcinoma (HCC) and other liver cancers. Responsibilities will include day-to-day management and coordination of this project, focusing on the intricate cross-talk between immune cells and specific ECM-associated proteins. By delving into the immunomodulatory properties of cancer ECM proteins, your work aims to unravel how the ECM shields tumours from the immune system and can regulate local responses to immunotherapies, such as checkpoint receptors.

We Are Looking For:

• An enthusiastic and motivated post-doctoral scientist.
• Strong background and experience in cancer immunology, preferably expertise in working with human samples.
• Knowledge of liver immunology advantageous, along with an interest in ECM research.
• Good publication record.

Your Impact:

You will be pivotal in performing and driving forward this research project: data collection and analysis, literature review, manuscript preparation for high-impact publications. Additionally, you will have the opportunity to showcase your findings at internal and external scientific meetings/conferences. Acting as mentor and supervisor, you will also guide and inspire junior members of the research team and visiting students.

Why Join Us?

• Be part of a vibrant research community with access to state-of-the-art laboratory facilities.
• Collaborate with leading experts in liver research at RW-IoH and King's College London.
• Contribute to cutting-edge projects focused on Liver Cell Injury and Repair, spanning various areas such as viral hepatitis, hepatocellular carcinoma, liver tissue engineering, and more.
• Leap into a world of groundbreaking liver research and be at the forefront of discoveries to reshape the future of cancer treatment.

Apply now and join us in our mission to deliver research that has tangible benefits for patients with liver disease.

The RW-IoH is an independent research organisation in partnership with King’s College London, with close research links with King’s College Hospital. Research is organised within the overall theme of Liver Cell Injury and Repair, and recent major areas of research have included viral hepatitis, hepatocellular carcinoma, liver tissue engineering, complications of cirrhosis, liver-gut axis, chronic and acute liver disease, and liver immunology. For more details:  http://www.liver-research.org.uk 

To apply: send a 1-page covering letter explaining your background and suitability, together with a detailed CV describing your research experience to date and including names and contact details of two referees, one of whom is the current/most recent employer, to:

James Poynton, Chief Operating Officer, Foundation for Liver Research via the 'Apply' button above.

Please name documents you send as follows:

<surname, first name, RS64, {CV}or{covering letter}>             Quote Job Ref: RS64

Informal enquiries: Dr Luca Urbani, Principal Investigator: luca.urbani@researchinliver.org.uk                                      

The Roger Williams Institute of Hepatology and the Foundation for Liver Research are committed to fostering a safe and welcoming working environment where everyone feels valued.

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