Research Associate (Fixed Term)

We are seeking to appoint a Research Associate to join the McEwan Group at the UK Dementia Research Institute at the University of Cambridge. 

The post is a fixed term study in collaboration with the ARUK Drug Discovery Institute. 

The successful candidate will research the ability of E3 ubiquitin ligases to degrade cytosolic protein aggregates in neurodegenerative diseases. They will build from recent discoveries that the antiviral receptor TRIM21 can evoke a potent degradation response against tau (Benn et al 2024 39208111), to uncover the range and requirement of ligases that can drive aggregate responses. Newly identified ligases will become the subject for collaboration with DDI for medicinal chemistry approaches. 

For informal inquiries regarding the role, contact Dr William McEwan wm305@cam.ac.uk  The role will be based at the UK DRI, Island Research Building Cambridge Biomedical Campus, CB2 0AH  

The University values diversity and is committed to equality of opportunity. We particularly encourage women and/or candidates from a Black, Asian and Minority Ethnic background to apply for this vacancy as they are currently under-represented at this level within our University. 

The University has a responsibility to ensure that all employees are eligible to live and work in the UK. 

Fixed-term: The funds for this post are available until 28 February 2027 in the first instance. 

To apply online for this vacancy and to view further information about the role, please click on the apply button above.

Applicants must have (or be close to obtaining) a PhD. 

Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £34,132) moving to Research Associate (Grade 7) upon confirmation of your PhD award. 

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. 

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager. 

Please quote reference ZE45925 on your application and in any correspondence about this vacancy. 

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. 

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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