Research Assistant

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
This is an exciting opportunity for a Research Assistant to work on a project exploiting glycans to develop new treatments for bone metastasis. The project is funded by the Prostate Cancer Research and Breast Cancer Now Bone metastasis collaboration fund and will run alongside other projects in our lab (see: www.munkleylab.co.uk).

Bone metastasis is a common incurable consequence of both prostate and breast cancer that causes severe pain and fractures and can be devastating for patients. This project will exploit newly developed glyco-immune checkpoints to develop new urgently needed treatments for breast and prostate cancer patients with bone metastasis.

The Research Assistant will use immunohistochemistry to monitor glycans and Siglec receptors in clinical samples from patients with bone metastasis. Alongside this, we will perform pre-clinical evaluation of therapeutic antibodies to test if they can stop tumours growing in bone. The project will utilise a range of in vitro and in vivo models of breast and prostate cancer (including immune cell co-cultures and in vivo mouse models) and includes a collaboration with an industrial partner.

For more information see: PMIDs: 38772281, 36725887 and 37550801.

This post is fixed-term for a period of 18 months.

For informal enquiries contact: jennifer.munkley@newcastle.ac.uk.

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/.

Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles.  These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

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