Postdoctoral Research Assistant in Neurodegeneration

Location: Centre for Medicines Discovery, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ

We are seeking to appoint a Postdoctoral Research Assistant in Neurodegeneration to join the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) at the Centre for Medicines Discovery.

ODDI is one of three research institutes funded by Alzheimer’s Research UK and charged with uncovering novel therapeutic approaches for dementia.

The research at the ODDI is focused on molecular mechanisms underpinning innate immunity and organelle homeostasis, which have been revealed by human genetics studies to be hot-spots that harbour many risk alleles for Alzheimer’s and Parkinson’s disease.

Our mission is to de-risk novel therapeutic approaches so that they are fit for further discovery investment. Consequently, we work closely with pharma and biotech companies and operate industry-style project teams to deliver our target validation and translational goals.

You will be responsible for the culture and preparation of cell lines and human iPSC derived cultures. You will run cellular assays to validate targets and determine target engagement. You will work to deadlines and show good attention to detail. You can expect, within a short space of time, to become proficient in several platforms and able to provide technical advice to students and colleagues within the ODDI, or collaborating academic groups.

It is essential that you hold a relevant PhD/DPhil (or be close to completion) in Neuroscience, Biochemistry, Pharmacology, Cell and Molecular Biology or Immunology. You must have excellent practical expertise in cell culture and in vitro assays and hold previous laboratory experience in molecular biology. You must have the ability to manage your own research with an eye for detail and take responsibility for administrative activities such as management of lab reagent stock, lab book writing.

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.  

This position is offered full time on a fixed term contract until 30 April 2031 and is funded by the Alzheimer’s Research UK

Only applications received before 12 midday on Wednesday, 22 July 2026 will be considered. Please quote 187006 on all correspondence.

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