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Research Associate in Synthetic Biology & Enzymology: Discovery and Engineering New Biosynthetic Pathways to Next Generation Antibiotics

The University of Manchester - Manchester Institute of Biotechnology

Location: Manchester
Salary: £32,816 to £40,322 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 3rd December 2019
Closes: 6th January 2020
Job Ref: S&E-14937

Job Reference: S&E-14937
Location: Oxford Road, Manchester
Closing Date: 06/01/2020
Salary: £32,816 to £40,322 per annum
Employment Type: Fixed Term
Faculty/Organisational Unit: Science & Engineering
Division: Manchester Institute of Biotechnology
Hours Per week: full time
Contract Duration: Available asap until 31 December 2021

Applications are invited for a Postdoctoral Research Associate to work with Professor Jason Micklefield at the Manchester Institute of Biotechnology (MIB,, for two years starting from January 2020. The project is funded by the Royal Society International Collaboration Awards and will involve collaboration with Professor Roberto Berlinck, Universidade de Sao Paulo in Brazil.

The project aims to discover, characterise and engineer new biosynthetic pathways to next generation antibiotics that are urgently required to combat antimicrobial resistance (AMR) and to treat neglected tropical diseases (NTD) in the developing world. We will focus on pathways to nonribosomal peptide and polyketide natural products. New approaches will be developed for engineering nonribosomal peptide synthetase (NRPS), polyketide synthase (PKS) and tailoring enzymes to create antibiotic assembly lines in Streptomyces or related bacterial hosts.

You will join a large interdisciplinary team of biologists and chemists in the MIB. Funding is also available for travel to visit collaborators in Sao Paulo, Brazil. You must hold a PhD, or have equivalent postdoctoral experience in enzymology/biochemistry and/or molecular biology/microbial genetics.

For further information about research in our lab see:

As an equal opportunities employer we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies

Enquiries about vacancy shortlisting and interviews:

Name: Professor Jason Micklefield


Tel: 0161 306 4509

Technical support:


Tel: 0161 850 2004

General enquiries:


Tel: 0161 275 4499

This vacancy will close for applications at midnight on the closing date

Please see the link below for the Further Particulars document which contains the person specification criteria.

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