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Research Assistant in Endogenous DNA Damage by Aldehydes

University of Oxford - Radcliffe Department of Medicine

Location: Oxford
Salary: £29,176 to £34,804 per annum, Grade 6
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 11th June 2021
Closes: 28th June 2021
Job Ref: 151603

Location: Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, John Radcliffe Hospital, Headington, Oxford, OX3 9DS

An exciting opportunity has arisen for a highly motivated and ambitious Research Assistant to play a key role in research of Endogenous DNA damage. You will be based in the in the Patel laboratory and will work with Professor KJ  Patel and other investigators in the MRC Molecular Haematology Unit.

The Patel lab is a world renowned lab researching the sources of endogenous DNA damage in blood stems. Recent studies have identified simple aldehydes such as acetaldehyde (by-product of alcohol breakdown) and formaldehyde as potent sources of endogenous DNA damage. However, little is known where these aldehydes come from, how they damage DNA and what are the cosequences of this to a mammal.

You will hold a degree (1st or 2:1 or equivalent) in a relevant area of science with some relevant laboratory experience. Research experience in a relevant field of genome stability and DNA repair, tissue culture, live-cell imaging and protein biochemistry are essential.  You will also have excellent communication, organisational and time-management skills, with evidence of a methodical and careful approach laboratory work.

This is a full time position, fixed term until 31/05/2022, funded by Cancer Research UK.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is 12 noon on Monday 28 June 2021.

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