Research Fellow in Structural Biology (CryoEM/MS) - DNA Repair and Huntington's Disease

Fixed Term: The post is available for one year in the first instance with possibility of extension.

This is an exciting opportunity to join the lab of Professor Konstantinos Thalassinos, based at University College London.  The main purpose of the position is to undertake the structural characterisation of protein complexes involved in DNA repair. This project follows on from our recently published work (Goold et al., Cell Rep. 2021 Aug 31;36(9):109649) where we identified new protein interactions important for modulating CAG repeat expansion, a key driver of HD pathogenesis. The position will suit someone with an interest in DNA repair, Huntington's disease, Cryo-electron microscopy and Structural Mass Spectrometry. The post is funded by the CHDI Foundation (https://chdifoundation.org).

The successful individual is expected to produce independent and original contributions to the project.  In addition to developing and conducting the research, the successful candidate will communicate results as scientific papers and in scientific presentations at local, national and international conferences.

The post is available for one year in the first instance with possibility of extension.

You should have a PhD in Structural Biology or a related discipline, with significant experience in single-particle cryoEM, and computational image analysis, data collection and processing, and a strong background in structural biology. Training in structural mass spectrometry approaches will be provided.

Please note: Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (Salary £32,217 - £33,958 per annum, including London Allowance) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis (including corrections).

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

For informal enquiries about the post please contact Professor Konstantinos Thalassinos at k.thalassinos@ucl.ac.uk.

If you have any queries regarding the application process please contact Biosciences staffing at biosciences.staffing@ucl.ac.uk quoting the vacancy reference number: 1884503.

Latest time for the submission of applications: 23:59.

UCL Taking Action for Equality

We will consider applications to work on a part-time, flexible and job share basis wherever possible.

Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.

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