Higher Scientific Officer (ID 505)

Job Details

Under the leadership of Prof Manuel Salto-Tellez, and led by Dr Tom Lund, we are seeking to appoint a Higher Scientific Officer to join the Integrated Pathology Unit. The right candidate will support all aspects of histopathology related to a range of research projects in our established, advanced translational research laboratory in the field of complex (IHC/RNA-ISH/mIF) tissue hybridisation technologies. The post holder will work alongside a team of Biomedical Scientists and other two Research Assistants/HSOs. The right candidate is expected to perform a variety of tasks that may include, but are not restricted to: a) Staining of pathology slides using manual and automated methodology; b) Scanning of pathology slides stained using a variety of methods e.g. HE, IHC, mIF; c) Annotation of pathology images, including QA/QC of image quality; d) Stitching of image files using image analysis software such as INFORM or HALO; e) General data analysis.

Key Requirements

The successful candidate must have a postgraduate degree in Biological Sciences, Cancer Biology, Molecular Biology, Molecular Pathology, or a similar discipline.  Knowledge of the current literature in cancer and molecular biology are also essential. A PhD level of education (or relevant extensive experience) is highly desirable. The right candidate will be passionate about improving outcomes for patients with cancer and an experienced researcher in the key techniques we employ, with an ability to learn and implement new technologies and approaches as they develop. He/she will be independent, capable of working in a laboratory with a consistent high standard and be able to ensure the scientific quality of the data produced by the IPU. The appointee will be keen to contribute his/her own ideas to the direction of research in the group and play a role in maintaining a supportive and collegiate team environment, as well as potential contributions to research papers and grant proposals. 

Applicants must have good laboratory skills, with experience in working in a collaborative environment. Experience in tissue handling and processing, histological techniques, immunohistochemistry, microscopy and digital image capturing is essential, as is the experience of using and maintaining SOPs based on these techniques. Experience with training other members of staff is also required. Hands-on experience with using the Leica Bond 3 and/or the Akoya PhenoImagerHT would be desirable. 

Department/Directorate Information

The Integrated Pathology Unit (IPU) is a joint venture between The Institute of Cancer Research (ICR) and the Royal Marsden Hospital (RMH), running an advanced translational tissue hybridization and digital pathology operation, with strong collaborative research and engagement with industry at its core.
Headed by Prof Manuel Salto-Tellez, and led by Dr Tom Lund, the IPU is a tissue-based laboratory with the mission to develop complex and highly quantitative approaches to tissue analysis (wet lab and in-silico) in the space of translational and clinical research, thus applicable in the context of clinical trials and adoption into diagnostic applications.

https://www.cancerbrc.org/integrated-pathology-unit 

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Tom Lund via Email at tom.lund@icr.ac.uk  

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