Higher Scientific Officer - Molecular Biomarkers & Clinical Translation (Prof Nick Turner) (ID427)

Job Details

Under the leadership of Professor Nicholas Turner, we are seeking an enthusiastic and motivated Higher Scientific Officer to contribute on technical delivery of biomarker analyses, as part of a team, for ongoing clinical trials and research projects.

Part of the Molecular Oncology team based in The Ralph Lauren Centre for Breast Cancer Research, this is an exciting opportunity for the successful candidate to use their skills in molecular biology in an interdisciplinary laboratory. The work will primarily be in relation to the delivery of high-quality analyses for research projects and clinical trials.

Key Requirements

Candidates should possess a minimum of a BSc in molecular biology or biomedical sciences or genomics or other related subject and should have experience of working in medical research or in a hospital environment. Knowledge of the biology, pathology and histological appearances of human breast cancer would be an advantage. Demonstrable knowledge and experience within cancer genetics, including techniques such as DNA and RNA extraction, PCR and next generation sequencing. Experience in ctDNA analysis and immunohistochemistry is desirable.  

Department/Directorate Information

The Breast Cancer Now Toby Robins Research Centre at the ICR, led by Professor Andrew Tutt, is the first centre in the UK entirely devoted to breast cancer research. Our goal is to advance research into the causes, diagnosis and treatment of breast cancer. Hosted within the Division of Breast Cancer Research, the Breast Cancer Now Research Centre consists of nine different teams, all working on different aspects of breast cancer biology, and is located in state-of-the-art laboratory space, with excellent core facilities and funding.

The Ralph Lauren Centre for Breast Cancer Research, based in the Royal Marsden Hospital NHS Foundation Trust and led by Professor Nicholas Turner, is a world-renowned laboratory that conducts translational research into breast cancer. The Centre’s aim is to make practice-changing advances in the medical management of breast cancer to improve patient outcomes and care. Major research themes include the personalisation of breast cancer therapy, identification of intra-tumoural heterogeneity and work to define its role in the emergence of drug-resistance and implementing in the clinic assays of circulating tumour DNA and other non-invasive assays of breast cancer.

The Centre also focuses on the characterisation of molecular changes resulting from hormone therapies, and predictors of risk of recurrence. The Centre has strong ties with The Institute of Cancer Research and benefits from both the scientific excellence of this Institution and the ground breaking clinical innovations at The Royal Marsden.

 We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Ruth Sardinha via email on ruth.sardinha@icr.ac.uk.

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