Postdoctoral Researcher

The post holder will join a research group led by Dr Michael FitzPatrick and will also be under the guidance of a wider human immunology research group led by Professor Paul Klenerman. The role will involve leading and delivering an exciting programme of research as part of the BREAD study. This multi-modal biomarker study will use proteomics, RNA sequencing, and single cell RNA sequencing to develop new and robust biomarkers for intestinal damage in coeliac disease. You would work in the Translational Gastroenterology Unit (TGU), which is part of the Nuffield Department of Medicine, Experimental Medicine Unit at the University of Oxford and is a large, collaborative laboratory embedded within the John Radcliffe Hospital. In addition, you would have primary responsibility for managing your own academic research and administrative activities, meaning you will demonstrate that you can project manage and have the ability to meet deadlines. You will also be expected to adapt existing and develop new scientific techniques and experimental protocols. This will be achieved by testing hypotheses, contributing ideas for new research projects, developing ideas, and collaborating with other senior researchers.

You will also need to act as a source of information and advice to other members of the group on scientific protocols and experimental techniques, including training and supervision of research assistants and students.

You will hold a relevant PhD/DPhil, together with experience in biological sample preparation, proteomics flow cytometry, genomic library preparation, and different data analysis approaches. It is essential that you have excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings. Experience of single-cell RNA sequencing is desirable.

The post is full-time and fixed term until 31^st December 2024.

Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application.

Only applications received before 12:00 midday on 17/04/2023 will be considered.

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