Research Assistant/Associate (MN KRUK )

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Salary
Research Assistant: £32,546 - £34,132 per annum.
Research Associate: £35,116 per annum.

The Role
We have an exciting opportunity for an experienced researcher to join our team.

You will be part of the Complement Therapeutics Research Group which is part of the Translational and Clinical Research Institute and the I&I theme. The CTRG focuses on understanding the role of the complement system in health and disease and your role will be to run normothermic machine perfusion (NMP) studies using human kidneys donated to research.

Our recent data demonstrated successful delivery of homodimeric minimal Factor H during the cold flush period of the organ transplant pathway, which protected human organs for damage. That next steps toward clinical trials are detailed safety analysis of HDM-FH. This project will use NMP to model drug delivery and release. Experimental models will assess immunogenicity and establish if HDM-FH is ‘best-in-class' to protect organs in this way.

Working as part of a multidisciplinary team you will manufacture the drug and so tissue culture experience is essential along with experience of in vivo imaging, histology, western and ELISA. You will also be required to be available when organs become available. Significant practical experience in NMP and knowledge of in vivo modelling would be a distinct advantage. A PhD in a related subject is essential for Research Associate or close to submission for Research Assistant.

This is a full-time post fixed-term for a period of 2 years.

For informal enquiries contact: Kevin Marchbank, Kevin.Marchbank@ncl.ac.uk.

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/.

Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of Research Role Profile  These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

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