Research Assistant- Twigger Group (Fixed Term)

The Cambridge Lactation Laboratory (https://www.cambridgelactationlab.com/) is seeking an enthusiastic and motivated Research Assistant to support the Cambridgeshire Multiomics of Milk (CAMB MOM) study. Join a dynamic and growing research group in the Department of Biochemistry and Pharmacology, under the leadership of Dr Alecia-Jane Twigger. The team is passionate about women's and infant health and specializes in both experimental (wet lab) and bioinformatic (dry lab) research. Within the group, we will provide you with further training in these disciplines. We would also support interested candidates to pursue postdoctoral studies (i.e. PhD).

The CAMB MOM study conducts multiomics analyses (lipidomics, metabolomics, proteomics, and transcriptomics) on samples from a cohort of breastfeeding participants in Cambridgeshire. The insights gained from gene-gene interaction networks will be tested using in vitro mammary organoid models and integrated into computational models. By investigating the molecular pathways of human milk production, we aim to resolve breastfeeding challenges and promote optimal long-term health for mothers and infants.

Candidate Requirements:

We seek a competent individual with excellent laboratory skills in building computational models and some wet lab experience. Preferred qualifications include:

• Knowledge of BMA executable models
• Experience with molecular analysis (e.g. RNA extraction and purification) and cell culture -The ideal candidate will demonstrate responsibility, initiative, independent thinking, and possess excellent communication and organizational skills. The ability to work effectively both individually and within a diverse team are highly desirable.

Key Responsibilities

Supporting Study Sample Collections and Analysis:

• Organize sample collections with research group members and study participants.
• Process and store samples for analysis.
• Perform pre-processing and quality control on raw lipidomic, metabolomic, proteomic, transcriptomic and genomic data.
• Analyse and integrate different 'omics data to understand milk biosynthesis pathways.
• Apply machine learning methods and statistical approaches to explore and interpret data.
• Organise data and upload datasets to relevant open-source repositories.
• Collaborate with local and international partners to compare findings across cohorts.

Laboratory Operations:

• Write up research findings for presentation and publication.
• Continually update knowledge and understanding in the field and translate this knowledge of advances in the subject area into research activity.

Qualifications:

• BSc degree (or equivalent) in Biology, Biochemistry, Natural Sciences, or a related field.
• Practical research experience.

Why Join Us

Being part of the Cambridge Lactation Laboratory, you will have the opportunity to contribute your ideas to ongoing research. You will be able to engage with an opportunity-rich scientific and clinical research environment within the University of Cambridge and nearby Cambridge Biomedical Campus. You will also have the opportunity to expand your research network, engaging with the wider international research community. We are committed to fostering an inclusive and supportive environment that promotes intellectual curiosity and scientific excellence. We encourage applications from a diverse group of backgrounds and allow for flexible working hours.

Fixed-term: The funds for this post are available until 31 May 2028 in the first instance.

To apply online for this vacancy and to view further information about the role, please click the 'Apply' button above. 

Informal enquiries are welcome to be sent to Dr Twigger: ajt215@cam.ac.uk

For queries regarding the application process, please contact: personnel@bioc.cam.ac.uk

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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