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Post-doctoral Scientist in Cancer Immunology (Fixed Term)

University of Cambridge - Department of Pathology

Location: Cambridge
Salary: £36,024 to £44,263 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 7th December 2023
Closes: 31st January 2024
Job Ref: PK39710

We wish to recruit a highly motivated Postdoctoral Research Scientist to join the laboratory of Professor Klaus Okkenhaug within the Division of Immunology at the Department of Pathology, University of Cambridge (https://www.okkengroup.path.cam.ac.uk/).

The project which is funded by the MRC will explore the role of the PI3K pathway in T cells and how this can be manipulated to increase anti-tumour responses, particularly in the context of cancer metastasis.

The successful applicant will join a friendly and collaborative team of researchers with access to cutting-edge facilities and resources within the centre of Cambridge on the historic Tennis Court Road site. The applicant will gain exposure to experimental approaches in cellular and molecular immunology including conditional mouse genetics, in vivo genetic cell fate-tracking, molecular biology and high throughput RNA- and DNA-sequencing. The applicant will also have the opportunity to develop CRISPR/Cas9-based mutagenesis screens to discover novel mechanisms of immune suppression in the metastatic tumour microenvironment. The programme of work is based on a collaboration with the Roychoudhuri Group whose lab is next to the Okkenhaug lab, as well as with futher collaborations with the Thaventhiran group (MRC tox) and Halim group (CRUK CI).

The ideal candidate will be motivated, independent and enthusiastic, and have a PhD in immunology, cell biology, or a related field.

Experience with flow cytometry, cell culture, and molecular biology techniques and a track record of publications in peer-reviewed journals are desirable. Strong analytical and problem-solving skills, written and verbal communication skills, and the ability to work independently as well as part of a team are desirable. Having a Home Office Personal licence (PIL) or equivalent and experience with cancer models will be an advantage.

Fixed-term: The funds for this post are available for 5 years in the first instance.

To apply online for this vacancy and to view further information about the role, please click on the apply button above.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

For more information on the work of the Okkenhaug group, please visit https://www.okkengroup.path.cam.ac.uk/ or https://www.path.cam.ac.uk/research/immunology-division/okkenhaug-group

For informal enquiries, please email Professor Klaus Okkenhaug ko256@cam.ac.uk

This vacancy is real. In addition, this vacancy is being studied as part of the Action Research on Research Culture project (ARRC) Action Research on Research Culture

The ARRC team are investigating the effects of CV format on shortlisting. If you consent to take part in the study, the ARRC team will use information from the shortlisting process to understand the impact of different CV formats.

The recruiting academic will not be told whether you have joined the study so your choice about whether to take part in the study cannot influence the decision on who to appoint. 

Further details can be found in the 'Further Particulars' document.

If you have questions about the ARRC project, please contact: arrcproject@admin.cam.ac.uk

Please quote reference PK39710 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
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