Postdoctoral Research in Immunology

We are seeking a highly motivated Postdoctoral Research Scientist to join the group of Dr Yi-Ling Chen based in the CAMS Oxford Institute. The study will focus on investigating how lipid-reactive T cells and lipid antigens contribute to immune responses following Group A Streptococcus (GAS) infection, with implications for autoimmune diseases such as post-streptococcal glomerulonephritis (PSGN). 

As a Postdoctoral Research Scientist, you will primarily be responsible for the development, design, and execution of experiments in the project, focusing on mapping the molecular characteristics of immune cells involved in lipid presentation pathways using cutting-edge immunological and transcriptomic techniques, such as multicolour flow cytometry, in vitro T cell functional assays, as well as TCR sequencing, spatial and single-cell multi-omics. This research could deepen the fundamental knowledge and promote translational/preclinical development.

You must have a proactive and adaptable approach to work and willingness to collaborate and provide scientific and workplace guidance to colleagues, research assistants and students. Excellent record keeping, careful methodological work skills and the ability to meet deadlines are essential.

It is essential that you hold a PhD/DPhil (or close to completion) in immunology or a related field, alongside hands-on expertise in in vitro functional immunological assays, including T cell activation assays, co-culture systems, cytokine profiling (e.g., ELISA, multiplex bead arrays), and multicolour flow-cytometry. You will have experience with processing primary tissue and blood samples for ex vivo and in vitro assays, with relevant specialist knowledge and experience designing, executing, and analysing data from single-cell & spatial RNA/TCR-seq experiments.

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

This position is offered full time on a fixed term contract for 24 months and is funded by ERC.

Only applications received before 12 midday on 27 October 2025 will be considered. Please quote 181896 on all correspondence.

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