Postdoctoral Research Fellow: Gene Therapy for Neurofibromatosis Type 1 (NF1)

This is an exciting opportunity for a highly motivated and talented Postdoctoral Research Fellow to join our enthusiastic diverse team to develop cutting-edge Gene Editing Therapies for Neurofibromatosis Type 1 (NF1). NF1 is one of the most common inherited neurological disorders and we use a combination of Genetic, Molecular, and Biochemical approaches with both animal and human cell models to improve our mechanistic understanding of the disease and identify therapeutic targets.

About you

The successful applicant should have received (or expect to receive soon) a Ph.D. in a relevant subject, with strong proficiency in standard Molecular Biology Techniques, experience with Mammalian Cell Culture, familiarity with Next Generation Sequencing methods and Data Analysis and experience with commonly used Bioinformatics tools and Databases. Excellent written and verbal communication skills, as well as strong organizational skills are required.

About the role

The Postdoctoral Fellow will play an integral role in projects related to developing CRISPR-based genome editing therapeutics (including base and prime editing, as well as CRISPR activation) for individuals with NF1. The project will use Molecular Biology, Biochemical and Cell Culture Techniques, for the design, optimization and testing of genome editing technologies in human cell lines, including iPSCs. In addition to presenting their research findings in scientific papers and at conferences, the position offers opportunities to mentor research staff, graduate students and student interns as well as interact with collaborators and peers and forge new collaborations. 

The laboratory is located in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) in downtown Boston, MA https://walkerlab.mgh.harvard.edu/. MGH is the largest hospital-based research enterprise in the United States. The new hire will be appointed as a Research Fellow at the MGH with a joint appointment at Harvard Medical School. The post is available immediately. 

This position is graded on the NIH postdoctoral stipend scale, for which the salary range is £44,239 - £44,879 per annum depending on previous experience and credentialing. We will be able to assist non-US citizens or permanent residents with appropriate temporary visa applications through the Hospital’s international office. 

Interested applicants should contact Dr. James Walker jwalker@helix.mgh.harvard.edu with a cover letter, their CV and contact information for at least three references. 

Our commitment to Equality, Diversity and Inclusion

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives, and ideas, we choose to lead.

Applications from protected veterans and individuals with disabilities are strongly encouraged. 

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