Research Assistant (Philpott lab) Oncogenic Transcriptional Regulation in the Paediatric Cancer Neuroblastoma

in the UK each year.  Neuroblastoma arises from neuroblasts that fail to complete their normal developmental programme but are instead locked in a state of enhanced proliferation and inhibited differentiation.  The goal of the Philpott lab is to exploit an understanding of normal neuroblast developmental control to restart differentiation in neuroblastoma cells by targeting a key transcriptional network both genetically and with drugs.29,605

The Philpott lab are looking for an enthusiastic and reliable Research Assistant to join our collaborative research team in the Wellcome-MRC Cambridge Stem Cell Institute, a world-leading centre for stem cell research.  The successful applicant will work with scientists in the Philpott lab and will be an integral part of the team.  They will contribute to ongoing projects that are interrogating the transcriptional mechanism of action of inhibitors and drugs that can drive neuroblastoma tumour differentiation, with the aim of developing new therapeutic approaches for this terrible disease.  The Research Assistant will be contributing to this research programme working alongside postdoctoral associates to deliver experimental and other data outputs.  In addition, the role will involve support to ensure the smooth day-to-day running of the laboratory.  There are ample opportunities within the lab and the wider environment for personal and professional development.

The role holder will have a BSc or MSc in biological / biomedical sciences or a related scientific area and a strong understanding of mammalian cell culture and molecular biology laboratory techniques.  Previous experience in experimental laboratory work is desirable; in particular, expertise in tissue culture, general molecular biology techniques, western blotting and microscopy would be desirable for this position.  It is essential that the role holder is organized, able to work collaboratively as a member of a team and can communicate effectively and clearly.

Please contact Prof. Anna Philpott (ap113@cam.ac.uk) with any informal enquiries. 

Fixed-term: The funds for this post are available until 30 September 2024 in the first instance.

Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The closing date for applications is: 5th November 2023

The interview date for the role is: To be confirmed

Please quote reference PS38747 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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