Postdoctoral Research Associate (Microscopy)

Fixed term contract - To 31^st March 2025, with a view to extending; full time - 35 hours per week.

Pilizota, Waclaw and McNally labs at the University of Edinburgh seek a highly motivated Postdoctoral Research Associate (PDRA) to undertake research in microscopy.

The Opportunity:

Long-term infectious and inflammatory conditions, such as chronic rhinosinusitis, are a complex host-pathogen response that is often poorly understood because of the multi-scale nature of the interactions, and numerous physical and biological factors that are involved. This is an opportunity to work with an interdisciplinary team of researchers located at the University of Edinburgh and the University of Cambridge to build new experimental and conceptual frameworks required to gain a predictive understanding of such complex systems. You will work on the development of customised microscopy capabilities needed to study the role of bacterial attachment and growth (including in the form of biofilms) using a model “system” that will replicate the main features of chronic rhinosinusitis in a microfluidic device (including the shape and geometry of the host sinus cavity, as well as viscoelastic properties of the mucus). Time providing the system will include ciliated epithelial cells. Time providing, you will also have the opportunity to study the attachment and growth of Pseudomonas aeruginosa in this model system. The success of this project can pave the way for an interdisciplinary understanding of one of the most important interactions in all of biology.

Your skills and attributes for success:

• Expertise in customised microscopy (constructing customised microscopes not just using them)
• Expertise in customized software development for image and data analysis
• Familiarity in working with microfluidics
• Basic microbiology techniques
• Capable of working independently, but in synergy with the rest of the interdisciplinary
• Find an interdisciplinary environment both challenging and motivating

The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336. Is e buidheann carthannais a th’ ann an Oilthigh Dhùn Èideann, clàraichte an Alba, àireamh clàraidh SC005336.

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